Meiofauna are minute group of organisms, live in freshwater, estuarine and marine habitats with size range between 0.063mm and 0.5mm.The paper illustrates the abundance and biomass of meiofauna along the Southeast continental shelf of India during January 2005. The study area extends from the latitude 10o 59"N to 14o N and longitude 79o 58"E to 80o 24"E as four transects; Nagapatnam, Cuddallore, Chennai and Krishnapatnam. From each transects, meiofaunal samples obtained from 30m, 50m, 100m and 200m depth ranges to analyse depth wise variation of meiofauna and by using a glass corer of 2.5cm inner diameter and 30cm length. Generally biomass and abundance of meiofauna were decreasing towards depth. Along the study area, the wet weight of meiofauna was varied from 0.125mg/10sq.cm (Chennai,200m) to 2.624mg/10sq.cm (Cuddallore,30m). Nematodes and foraminiferans were contributing major part of biomass and abundance. Mean biomass along the entire area was 0.866mg/10sq.cm. Abundance of meiofauna was varied from 28No/10cm2 (Chennai,200m) to 782No/10cm2 (Cuddallore,30m). The abundance was minimum in 200m and maximum in 30m depth ranges. It shows a decreasing trend with increasing depth. The average numerical abundance along the entire field was 223No/10cm2. Ten meiofaunal groups were identified; major groups were Nematoda, Foraminifera and Copepoda.