The novel detection of brevetoxins in Australian waters presents a new challenge to seafood safety. This risk is actively managed through ongoing monitoring of toxin levels in seafood to support market access decisions and protect public health. While current monitoring is conducted using advanced chemical techniques (liquid chromatography coupled to mass spectrometry), there are several commercially available brevetoxin test kits currently on the market that promise reduced cost and faster sample throughput. However, their suitability for Australian conditions has not yet been assessed. We therefore explored the performance of four select kits to detect brevetoxins in five different seafood matrixes, including pipi, mussel, oyster and abalone tissues. Through careful consideration of test kit cross-reactivities, toxin profiles, detection rates (determination of false positive and false negatives), as well as additional usability criteria, the most suitable candidate test was identified. Using this test kit as an example, this talk will explore how such tests could be best employed for on farm decision making to manage business risk, as well as discuss the steps required to successfully implement their use as screening tests in routine monitoring programs.